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Pharmacological Research, 64 (2), 162-168

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DJ-1, which is predominantly expressed in human astrocytes, exerts multiple neuroprotective effects by regulating oxidative stress, maintaining mitochondrial function, and modulating anti-inflammatory responses (Miyazaki and Asanuma, 2020)

Inflammation also plays a critical role in the relationship between mitochondrial dysfunction, CVDs, and cognitive impairment