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Both classes of enzyme are involved in a wide range of red-ox reactions and includes the same critical thiamine-dependent enzymes described above, the pyruvate dehydrogenase complex (PDHc), 2-oxoglutarate (-ketoglutarate) dehydrogenase (OGDH), and branched-chain -ketoacid dehydrogenase (BCKD)

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Abstract Ferroptosis is an iron-dependent, lipid peroxidation-driven cell death pathway, while Parkinsons disease (PD) patients exhibit iron deposition and lipid peroxidation in the brain

Because of this, they are not recommended for people who have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia

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