Some patients experience temporary gas as digestion slows and the gut adjusts to hormonal changes
The hope was that once we have oral agents, theyre going to be less expensive than the injectable, because some of the justification for the higher cost of the injectable was the mode of delivery, the pens, says Rozalina McCoy, an endocrinologist and internist at the University of Maryland School of Medicine.* Even though Im not surprised, I am disappointed that the oral treatment, which doesnt have that higher cost, is going to be a [similar] price for patients. McCoy is also concerned that the relative ease of accessing the pills may increase their off-label use among people who do not have obesity
But medications leading to so much weight loss may be needed for people with severe obesity (a BMI of 35 or more) or the 10% of patients who dont respond to GLP-1 medications and need something more powerful, Azar said
Species-specific regulation of innate immunity by vitamin D signaling
Acknowledgements The author thanks Dr
A Global Review on Short Peptides: Frontiers and Perspectives