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Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, Ghissassi FE, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Cogliano V

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Acromegaly results in excess growth hormone production

Two primary drivers of profibrotic activity have been identified: excessive or prolonged inflammation and premature or anomalous tissue tension

Under this influence, Bcl-2 protein is rendered inactive