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When oxidative stress occurs, Nrf2 dissociates from Keap1 and translocates to the nucleus, where it binds to antioxidant response elements (AREs) in the promoter regions of specific genes, initiating their transcription process (170)

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100 mL of ether was added to the reaction solution which was then stirred to obtain solids

This context can support provider discussions about whether standard titration timing aligns with your anticipated biology, though genetics do not predict exact outcomes