D-Allulose, a stereoisomer of D-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: a new candidate dietary restriction mimetic
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MDMA and tramadol or tapentadol co-administration causes serotonin-independent neurological damage DOI: Keywords: MDMA, tramadol, tapentadol, serotonin, in vitro, acute neurotoxicity Abstract The simultaneous consumption and misuse of different drugs, including 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and opioids, raise concerns about fatal intoxications, as a result of increased serotonin levels
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We found that glutathione (GSH) levels were associated with MTX resistance in both treated and untreated cells, suggesting a new constitutive metabolic-based mechanism of resistance to the drug
Tirzepatide, a dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist, exhibits favourable effects on pancreatic -cells and hepatic steatosis in obese type 2 diabetic db/db mice