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Hepatic encephalopathy: from metabolic to neurodegenerative

Hepatology 2008

Live cell image processing Translocation of Nrf2-GFP to the nucleus and accumulation of HMOX1-GFP and SRXN1-GFP expression was monitored by a Nikon TiE2000 confocal laser microscope equipped with an automated focus system

doi: 10.1096/fj.202001807

GSH activity is facilitated by activation of the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 that regulates expression of genes controlling antioxidant, inflammatory and immune system responses

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