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Kidney Int Suppl 69:S93-106 Mercadal L, Coudert M, Vassault A, Pieroni L, Debure A, Ouziala M et al (2012) L-carnitine treatment in incident hemodialysis patients: the multicenter, randomized, double-blinded, placebo-controlled CARNIDIAL trial

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Yes, alcohol can reduce medication effectiveness by interfering with liver metabolism, increasing blood sugar variability, and disrupting the appetite-suppressing signals that make GLP-1 therapy work

Cellular Biology 5, 628633