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5-Amino-1MQ is a small-molecule quinolinium compound not a peptide that selectively inhibits nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme involved in the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor

GLP-1s show promise for metabolic and mental health In questioning how GLP-1 therapies may alter mood, this study not only provided preclinical causal evidence but also a potential therapeutic target

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