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Bran D, Dvorsk D, Strndel J, Matkov T, Halaov E, kovierov H

Although our data align with the notion that inhibiting NMDA receptor signalling in the hypothalamus decreases food intake and body weight 8,40 , earlier studies have demonstrated that NMDA receptor antagonism in the brainstem attenuates vagus-mediated meal-related satiety 6,7,42

Crucial role of the melanocortin receptor MC1R in experimental colitis

But if this is the only data we have, thats what we have to work from