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Reactive oxygen species (ROS) act like sparks in a dry forest, igniting a blaze of tissue damage

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This shift leads to an increase in reactive oxygen species (ROS) production and depletes glutathione (GSH), a crucial antioxidant in hepatocytes (Chen et al ., 2018)

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Pancreatic islet tissue disorder induced by fibrosis is another important mechanism of -cell failure [7, 31]

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