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A 2025 systematic review found that 35 of 36 BPC-157 studies were conducted in rodents, and the single human study was a small, uncontrolled retrospective analysis of 12 individuals

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The H6PD gene is located on chromosome 1p36.22 and is composed of 7 exons that generate two alternatively spliced mRNAs encoding precursor proteins of 802 amino acids (isoform 1) and 791 amino acids (isoform 2)

The researchers successfully increased bFGF brain supply via the non-invasive IN route, and hemiparkinsonian rats demonstrated a considerable neuroprotective improvement [127]