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Conversely, if you experience energy changes or gastrointestinal symptoms at night, morning injection may improve sleep quality

If you are currently on injectable tirzepatide and wondering whether the switch to sublingual makes sense, discuss it with your prescriber

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Tirzepatide mimics two hormones: GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)

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Serine phosphorylation of IRS-1 (at residues s312/s616/s636) deactivates and decouples insulin signalling, and thus elevated expression of IRS-1 s312 is recognised as a proxy marker of NInsR 1113