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Energy and macronutrient intake in growth hormone-deficient adults: the effect of growth hormone replacement

Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males

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Cell 169 , 132147 (2017)

The compound's ability to activate multiple pathways simultaneously represents a paradigm shift from earlier single-mechanism approaches

The constant levels of marker proteins such as GAPDH, combined with observations indicating that knockdown of the UPR element, BiP/Grp78 , revealed no detectable effects on Nrf2, GCLC, or glutathione, further support the conclusion that NFT-mediated stabilization of Nrf2 is a major contributor to its accumulation and the subsequent stimulation of GCL and glutathione synthesis