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Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization

Reading a Fish Oil Label for Safety Look for: EPA + DHA content listed per serving (not just "fish oil" in mg, which includes fats other than EPA/DHA) Absence of added retinol or vitamin A in the supplement facts panel Third-party certification (USP, NSF, or IFOS) for purity and heavy metal testing, relevant because isotretinoin already taxes the liver A supplement showing 1,000 mg fish oil per capsule may contain only 300 mg combined EPA+DHA

Curr Pharm Des 31(37):29592971

Zhao S, Qu Z, Wang L, Gu P, Mou J, Yang S, Wu H

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Forman, Zhang & Rinna (Mol Aspects Med, 2009) review measurement and protective roles without establishing standard infusion protocols