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In some embodiments, the otic formulation or composition comprises about 0.01% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

The primary goal was to evaluate the safety and tolerability of tirzepatide over the treatment period

(1985) observed that men on a low-calorie diet (1,200 kcal/day) for 8 weeks experienced a 30% reduction in total testosterone levels

however, over-expression of GPX4, could reduce the brain water content and improve neurological behavior by suppressing ferroptosis (Gao et al., 2020)

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging