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You may find yourself wondering if you can stretch your doses or if you can take Wegovy once a month instead

While mice and rats do not vomit, GLP-1R agonism induces emesis in the musk shrew and is associated with an increase in cFOS staining in the AP, nucleus of the solitary tract (NTS), DMH, VMH, lateral hypothalamus (LH), and PVH that is blocked by GLP-1R antagonism (77)

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Are There Any Important Safety Considerations

Nanoparticle formulations of the Parkinsons drug, selegiline, resulted in 12-20 fold increases in brain concentrations in laboratory animals compared to delivering the drug orally

The lysate was subsequently centrifuged (12000 g, 4 C, 5 min), denatured, analysed by SDSPAGE, and transferred to PVDF membranes (IPVH15150, Millipore)