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1.4.3 Limitations of benign and VUS classifications Ultimately, WES is not a genetic oracle, and in contrast to Mendelian diseases which often result from single-gene coding variants (Botstein and Risch, 2003), several complex traits could be driven by noncoding variants that presumably affect gene regulation

Fractional lasers and deeper treatments may require a longer recovery period, where patients might experience skin peeling or scabbing as part of the natural healing process

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