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Zepbound ( tirzepatide ) is a dual glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 receptor agonist (GLP-1)

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By modulating the availability of inositol, researchers can study perturbations in the PI3K/Akt/mTOR pathway, which has profound implications for glucose uptake, glycogen synthesis, and cell survival

Additionally, recent studies have suggested a possible role for both GLP1-ra and SGLT2is in the management of diabetic retinopathy and DMO that extends beyond glycaemic control [10, 11]

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