Overall, these findings suggest semaglutide may modulate motivation to seek opioid reward and could be useful in the development of pharmacotherapies to address OUD
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Regular, moderate-intensity physical exercise has a positive effect on intestinal epithelial status and intestinal barrier integrity
Weight loss was also modeled as a continuous outcome (i.e., percent weight loss at each time point relative to index date measurement) and a binary outcome (i.e., percent of cohort achieving 5%, 10% and 15% weight loss at each time point relative to index date measurement)
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Action in Diabetes 5 met (2009) Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial