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In individuals with insulin resistance, as well as those with type 2 diabetes, there is an associated elevation in the circulating levels of the branched-chain amino acids (BCAA) leucine, isoleucine, and valine

Katsurada K, Yada T (2016) Neural effects of gut- and brain-derived glucagon-like peptide-1 and its receptor agonist

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Further analysis of signaling pathways confirmed that PD effectively upregulated endogenous TGF-/Nodal signaling and downstream Smad2/3 transduction, while concurrently downregulating BMP signaling, leading to robust DE formation

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