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As a potent antioxidant, Pyrroloquinoline quinone (PQQ) may also reduce lipid peroxidation, though its direct impact on GPX4 regulation remains further elucidated ( 4.3.2 Superoxide dismutase (SOD) and catalase (CAT) SOD and CAT are essential enzymes in the antioxidant defense system
Tirzepatide suits patients who want dual-receptor signaling or those with inadequate response to semaglutide alone
According to an article published in Diabetes Therapy , Co-infusion of GLP-1 and GIP has a synergistic effect, resulting in significantly increased insulin response and glucagonostatic (glucagon stabilizing) response, compared with administration of either hormone alone. In other words, combining GLP-1 and GIP receptor agonists in a single drug appears to have a greater impact on blood sugar control than GLP-1 used alone
doi: 10.1056/NEJMoa2212948 359 van LengerichB.ZhanL.XiaD.ChanD.JoyD.ParkJ
