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[79] However, mortality during hospitalization is high

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Mitochondria-dependent apoptosis pathway: metformin can induce the loss of mitochondrial membrane potential and release apoptosis-related factors such as cytochrome C, thereby activating the caspase cascade and ultimately leading to apoptosis (64, 65)

It has no specific L and R forms

Microglia from SLE mouse models show upregulation of genes involved in SR activity and downregulation of genes involved in inflammation and chemotaxis, suggesting that microglia in SLE-prone mice may not be able to regulate inflammation appropriately (311)

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Pandey P., Singh J., Achary V.M.M., Reddy M.K