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The median change in stroke volume during the three time points did not differ between the two groups ( p 2 mmol/l), with stroke volume change following passive leg raising over 10% (preload dependency), and with no contraindication to a nasogastric tube

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Dose, delivery, and concentration are fundamentally different

In animal models, visible effects typically appear after 4-6 weeks of consistent dosing, with long-term treatment producing weight loss and increased lipolytic sensitivity