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Howard SC, McCormick J, Pui CH, Buddington RK, Harvey RD

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[12] This mechanism slows gastric emptying (most notably early in therapy), prolongs feelings of fullness, and reduces hunger signals in the brain , leading to decreased food intake and subsequent weight loss

It is also more lipolytic, meaning it releases fatty acids easily

Cytotoxicity DMEM was unable to buffer the concentration ranges of each compound beyond 3.25 mmolL 1 due to the acidic nature of GSH and the synthesised compounds, which set the limit of drug concentration useable in the cell culture studies

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