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Tumor cells, tumor-associated macrophages, and certain dendritic cells can decrease local tryptophan levels by provoking metabolic enzymes, including indoleamine 2,3-dioxygenase (IDO1) and tryptophan 2,3-dioxygenase (TDO2) (130)

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Mitophagy is essential for regulating mitochondrial homeostasis, so we further interrogated the effect of CYP11A1 on mitophagy in this starvation-induced Mitochondrial destabilization process

[Google Scholar] 71.Sotirakopoulos N., Athanasiou G., Tsitsios T., Stambolidou M., Missirlis Y., Mavromatidis K