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In addition, the treatment of nicotinamide (NAM), a form of vitamin B3, suppressed the activity of sirtuin-1 (SIRT1), a regulator of cellular stress resistance, and peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1), a key transcriptional coactivator involved in mitochondrial biogenesis and energy metabolism
Experience-induced Arc/Arg3.1 primes CA 1 pyramidal neurons for metabotropic glutamate receptor-dependent long-term synaptic depression
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The anorectic effects of OXM are abolished in GLP-1R(-/-) mice and can be inhibited by exendin-(9-39)