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8 BrzywczyJ.NatorffR.SienkoM.PaszewskiA

Inject slowly: Depress plunger steadily over 35 seconds to minimize discomfort

59 NO can reversibly inhibit mitochondrial respiration at complex IV, whereas the more damaging peroxynitrite can permanently inactivate complexes I, III and V

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The situation is further compounded by the presence of posttranslational modifying factors, such as kinase activities and S -glutathionylation

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