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This is often due to the insufficient concentration of drugs that accumulate in the tumor site after absorption, as well as the severe adverse reactions caused by their non-selective killing effect on normal tissues, resulting in poor patient tolerance

Despite the lack of direct effect on neuronal viability, the age-associated reduction in D2 (Antonini et al., 1993) may be one of the reasons that age is a risk factor for PD

NOTE (1,2) (A) GLP-1 receptor agonist (RAs) drugs are synthetic versions of the natural GLP-1 hormone, modified to resist breakdown by the enzyme DPP-4

This peptide, works by binding to melanocortin receptors and activating the melanin-producing cells in the skin, as demonstrated in various dermatological studies

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