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Nature 583 , 290295 (2020)

This combinatorial approach aligns with the multi-target philosophy that makes peptide research compelling for mood disorders

And its all coming from a peptide you probably havent heard of

Upon arrival, mice were acclimated to housing at 22C24C under a 12-hour light/12-hour dark cycle with ad libitum access to irradiated water and a low-fat chow diet (LFD

Typically, injections are administered once or twice a week

Unlike peptide-based formulations made of amino acid chains, orforglipron is a small-molecule compound, allowing it to remain stable and effective in the acidic environment of the stomach