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At that time, the market was dominated by insulin pens from major manufacturers such as Novo Nordisk, Lilly and Sanofi and the first prefilled autoinjectors for the two anti-tumour necrosis factor (TNF) antibodies Humira (adalimumab, AbbVie) and Enbrel (etanercept, Amgen)

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Many side effects can be minimized or avoided by following proper precautions before and after treatment

Lastly, the closeness_centrality assesses how close a vertex is to all other vertices in the graph, while also considering the edge weights and normalizing the result

for the TB-500 deep dive, see What Is TB-500

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