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doi: 10.1038/s41430-021-00980-9

IL-17 inhibitors like secukinumab demonstrate rapid efficacy but pose risks of mucocutaneous infections, whereas IL-23 blockers like guselkumab offer longer remission but slower onset

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428 While hepatocyte metabolic reprogramming plays a crucial role in liver regeneration, the metabolic shifts in non-parenchymal cells are equally important and warrant further exploration

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Evidence suggests that metals like mercury, cadmium, and lead may provoke mast cell mediator release and microglial activation, especially in genetically susceptible individuals (Miller et al., 2021