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Individual response can vary due to baseline weight, diet, activity level, sleep, and underlying health conditions

Riss TL, Moravec RA, Niles AL, et al

Blood pressure was measured in anesthetized D 2 / mice treated with etamicastat by gavage, (10 mg/kg), conscious D 2 / mice, and D 2 +/+ littermates, and mice with the D 2 R selectively silenced in the kidney, treated with etamicastat in the drinking water (10 mg/kg per day)