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NAD+ is a direct substrate replenishing cellular pools (low oral bioavailability), whereas 5-Amino-1MQ is an NNMT enzyme inhibitor protecting existing NAD+ from degradation

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For studies investigating systemic or multi-tissue repair responses such as those modelling complex injuries or post-surgical recovery in animal systems the combination offers a broader pharmacological reach than either peptide in isolation

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that plays a central role in NAD+ metabolism and cellular energy balance

Vitamin B12 is vital for red blood cell formation, DNA repair, and nerve function