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This research specifically focused on people with type 2 diabetes, so more research is needed in other groups, and the results should not be generalized

The dosage for weight loss in non-diabetics varies and is tailored to individual needs, weight-loss goals, and any underlying health conditions

The average rate of regain for semaglutide and tirzepatide was approximately 0.8 kg (about 1.8 pounds) per month after discontinuation

The problem is that natural GLP-1 breaks down within minutes

Extreme neuroplasticity of Hippocampal CA1 pyramidal neurons in hibernating mammalian species

But research actually suggests that roughly a quarter of weight loss may come from lean mass, a category that includes muscle, water and connective tissue