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Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue

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It is also linked to cancer-promoting activity and chemoresistance [24]

35,36 Observed elevations in homocysteine in 3R3R individuals imply the methylation pathway is being hindered in favour of de novo thymidylate synthesis

Blood 138 (8), 689705