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Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system

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Fluid Retention and Heart Failure with Concomitant Use of PPAR-gamma Agonists: Fluid retention and heart failure can occur with concomitant use of thiazolidinediones (TZDs), which are PPAR-gamma agonists, and insulin, including NovoLog

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