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These findings suggest that endothelial IGF- 1R signaling is essential for maintaining skeletal muscle capillary density, and its deficiency leads to impaired vascular supply, potentially contributing to exercise intolerance and muscle fatigue in KD mice

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Examples: Fruits and vegetables like broccoli, spinach, berries, apples, and whole grains like oats, quinoa, whole-wheat bread

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VNN1 can impair insulin-secreting cells by increasing oxidative stress, potentially serving as a biomarker for early detection of pancreatic cancer-related diabetes [63]