Food Sci Nutr 9:747756 Kong L et al (2021) Sulforaphane ameliorates diabetes-induced renal fibrosis through epigenetic up-regulation of BMP-7
HGHs anabolic effects are mediated primarily through IGF-1, which then acts on peripheral tissues such as muscle and bone. Laron, Z., Pediatric Endocrinology Reviews IGF-1 LR3: Direct Muscle Growth Stimulator IGF-1 LR3 binds directly to IGF-1 receptors on muscle fibers, triggering: Muscle cell differentiation and proliferation Activation of satellite cells , essential for muscle repair and new muscle fiber growth Enhanced nutrient uptake (glucose, amino acids, creatine) Because of this direct action , IGF-1 LR3 can stimulate local muscle hypertrophy without relying on systemic conversion pathways
The cause is multifactorial: reduced caloric intake, slower gastric emptying, mild dehydration if water intake drops with appetite, and elevated B12 demand during a rapid metabolic shift
[DOI] [PubMed] [Google Scholar] 160.Bosman G.J., Barholomeus I.G., de Man A.J., van Kalmthout P.J., de Grip W.J
You dont get a B12 shot
Previous research has shown that increased intakes of individual antioxidants, such as vitamins A and C, and glutathione, can prevent the accumulation of free radicals and thereby reduce oxidative stress
