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It is not recommended for pregnant or nursing women, individuals under 18, or those with serious medical conditions

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Neuronal glucose uptake is predominantly facilitated by GLUT3, although other transporters such as GLUT2 and GLUT4 may be involved in glucose uptake into neurons under specific physiological or pathophysiological conditions (183)

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Its important not to double up doses to try and make up for a missed dose

Orforglipron is taken as a once-daily oral pill