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Better vascularisation of the regenerating tissue translated in models into more efficient repair

Biochemical and Biophysical Research Communications, 280(1), 132-138

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Of obvious relevance to our findings, GSTP1 has recently been shown to be an IL-6 target gene (Wang et al, 2010), while inhibition of GSTP1 activity by an IL-6 or IL-6 receptor mAb correlates with increased platinum (and paclitaxel) sensitivity in renal cancer cells (Mizutani et al, 1995)

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In experimental systems, this dual approach provides a more representative model of coordinated growth hormone regulation compared to isolated receptor activation