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In addition, its relevance continues to expand as new studies explore multi-pathway receptor interactions

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Aliment Pharmacol Ther 1991;5(2):115-25

By activating both GIP and GLP-1 receptors, tirzepatide enhances insulin secretion in response to elevated blood glucose levels, suppresses glucagon release (which reduces glucose production by the liver), slows gastric emptying, and promotes satietyleading to reduced calorie intake and weight loss