Problems in GLP-1RA development Cost-effective and reliable trial endpoints for MASLD medication Assessing long-term liver benefits in clinical trials has remained a complex issue
A group of genes that antagonize iron-dependent cell death, including GCH1 and its metabolic derivatives BH4/dihydrobiopterin (BH2), has been identified, and BH4/BH2 synthesis-induced lipid remodeling have been found to inhibit ferroptosis by selectively preventing the consumption of two polyunsaturated acyl-tailed phospholipids (59)
While weight loss might make people seek out GLP-1s, the drugs are still new and recent studies show that they can have negative side effects: 4 in 5 people feel mild to moderate stomach side effects like nausea, vomiting, and diarrhea
Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimers disease continuum
Selenoprotein T exerts an essential oxidoreductase activity that protects dopaminergic neurons in mouse models of Parkinson's disease
Ashwagandha Ashwagandha has long been hailed as the king of herbs for its ability to reduce chronic stress and anxiety