It preserves lean mass better than either approach, likely due to its effects on insulin signaling and muscle protein synthesis
doi:10.1074/jbc.M114.571521
It also stimulates nerve outgrowth, which plays a role in follicle cycling signals
It may be pertinent for clinicians to check carnitine levels with other routine diet therapy lab monitoring (at 3 months, 6 months, then every 6 months) since patients are often asymptomatic, and carnitine deficiency may go undetected if it is not checked
GHK-Cu has an extremely high affinity for copper(II), with a dissociation constant (Kd) of approximately 10 M, meaning the peptide-copper bond is exceptionally strong
Important Considerations and Limitations While the potential benefits of GLP-1 microdosing are promising, its crucial to acknowledge the current limitations: Lack of Clinical Guidelines Currently, there are no formal clinical guidelines supporting microdosing protocols