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We searched PubMed up until January 2025 for RCTs to identify potentially eligible studies, using the following search terms: ((((((myocardial infarction) OR (stroke or cerebrovascular accident)) OR (heart failure or cardiac failure)) OR (death OR mortality)) OR (Cardiovascular Diseases[Mesh])) OR (kidney failure)) AND ((lixisenatide or exenatide or liraglutide or semaglutide or dulaglutide or albiglutide or efpeglenatide or tirzepatide) OR (glucagon-like peptide-1 receptor[Mesh]))