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In an updated study, plasma miR-206 level stands out as a good prognostic biomarker to monitor MCI progression to AD over a period of 5 years (Kenny et al., 2019)
N6-methyladenosine (m 6 A) demethylase FTO is significantly upregulated in MPP + -stimulated SK-N-SH cells, which suppresses YTH domain family protein 2 (YTHDF2) expression, promotes m 6 A demethylation of BRCA1-associated protein 1 (BAP1) and enhances BAP1 expression, upregulates p53 expression, and inhibits SLC7A11 transcription, thereby increasing MDA, Fe 2+ , and 4-HNE levels and triggering neuronal ferroptosis
The remaining author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
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