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111 , QT (1050 M) was adequate to increase CYP11A1 promoter activity

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Outcome events of interest include time to: histological progression to cirrhosis, uncontrolled ascites, HCC, liver transplantation/transplant eligibility, and hospitalisation for hepatic decompensation or death.85 Key Point Currently OCA is being evaluated in a large phase III, randomised, placebo-controlled trial Elafibranor Elafibranor is another agent currently in phase III for the treatment of NASH