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doi: 10.1016/j.kint.2017.02.011 89

Tumor Biol 2013;34(6):3913-3922

It functions as a signaling molecule that modulates gene expression, primarily affecting genes related to collagen synthesis, antioxidant defense, and inflammation

Popp, S

It is a prominent proinflammatory cytokine which impairs insulin secretion and beta cell apoptosis leading towards T2D