Widely used weight-loss and diabetes drugs show clear benefits, but emerging evidence clarifies their side effects, rare risks, and what clinicians should monitor long term
While preclinical studies have provided important mechanistic insights into the CV effects of GLP-1RAs, many experimental models of atherosclerosis, MI, or heart failure were conducted in mice that, despite being fed an HFD or HCD, do not develop the severe obesity or T2D that characterize patients treated with GLP-1RAs in CVOTs
Her medical expertise has earned her prestigious distinction including the Patients Choice Award and Compassionate Doctor Recognition by Vitals
J., Stubbs, B., Mamas, M
Of note, many of the studies used a single-dose administration of GLP1RAs
A typical starting dose might be one teaspoon mixed in water once daily, eventually working up to the recommended dose on the package