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In Canadian men aged 70 and older, 41% are deficient in zinc
33 , e14104 (2021)
We advise against use in patients with active cancer, cardiovascular disease, autoimmune disorders, liver or kidney disease, clotting issues, pregnancy or breastfeeding, or those under age 20
This is especially important for non-liposomal versions, though liposomal formulas are much more flexible due to their protective lipid layer
This review provides a concise overview of new directions in treatment development for TRD, including treatments targeting the glutamate system, the opioid system, inflammatory signalling systems and others